ETHYL ACETATE EXTRACT OF Chenopodium murale ROOT, A SOURCE OF BIOACTIVE COMPOUNDS

  • Arshad Javaid Institute of Agricultural Sciences, University of the Punjab Lahore, Pakistan
  • Syeda Fakehha Naqvi Institute of Agricultural Sciences, University of the Punjab, Lahore, Pakistan
  • Iqra Haider Khan https://orcid.org/0000-0002-9559-8118
Keywords: of the compounds were antimicrobial in nature. Keywords: Chenopodium murale, Bioactive compounds, Ethyl acetate extract, Root

Abstract

            Chenopodium murale L. is a winter weed of Chenopodiaceae. In this study, bioactive compounds present in ethyl acetate fraction of root extract of C. murale were identified. The weed plants were collected from Jehlem, Pakistan. Its roots were dried, powdered and extracted in methanol. After evaporation of the solvent, the remaining extract was mixed in water and partitioned with n-hexane, chloroform and finally with ethyl acetate. The last fraction was analyzed through GC-MS that indicated the presence of 15 compounds. These included the three major compounds namely o-xylene (15.03%), cyclopentanol (13.42) and 2-hexanol (13.99%). The moderately and less abundant compounds were  ethylbenzene (5.47); methyl acetate (6.00%); cholestrol (4.33%); 2-phenanthrenol (3.01%); cyclohexanone (5.32%); p-xylene (5.12%); furostan-3,26-diyl dibenzoate (3.29%); dihexyl phthalate (4.99%); tricosanoic acid (2.74%); dioctyl phthalate (4.99%), hexanal (3.05%) and ergostane (1.29%). Literature survey showed that 10 of the identified compounds exhibited various biological activities including antifungal, antibacterial, antioxidant, anticancer and antipsoriatic. Most of the compounds were antimicrobial in nature.

Published
2021-03-29